Abstract Background Very long-chain acyl-coenzyme-A dehydrogenase deficiency is a rare, severe life-threatening metabolic disorder of mitochondrial fatty acid oxidation, caused by mutations in ACADVL gene.Here we present a genetically confirmed case of a South Asian baby girl with Course a pied - Homme - Chaussures - Light trainer severe, early-ons

The novel antimicrotubular taxane called cabazitaxel was developed to avoid the primary mechanism of resistance for docetaxel, the first-line treatment for patients with hormone-resistant prostate cancer (HRPC).However, its ability to increase the survival rate for HRPC is limited to a few months, and cabazitaxel-resistant prostate cancer was also

Programmed cell death is characterized by a cascade of tightly controlled events that culminate in the orchestrated death of the cell.In multicellular organisms autophagy and apoptosis are recognized as two principal means by which these genetically determined cell deaths occur.During plant-microbe interactions cell death programs can mediate both

BackgroundThe mechanisms of epigenetic regulation emerge as a fundamental determinant in the complex landscape of cancer initiation and advancement.However, the specific impact of epigenetic regulation on cancer progression remains unclear.To explore the relationship between epigenetic regulation and cancer progression, we utilized transcriptomic d